List of cell types and regions assayed

Cell types and regions assayed

Abbreviations used *

Cone cells

RetC.Cones

Rod cells

RetR.Rods

Hypothalamus

Hyp

Hypocretinergic neurons of hypothalamus

Hyp.Hcrt

Basal forebrain

BF

Cholinergic neurons of basal forebrain

BF.Chat

Brain stem

BS

Cholinergic neurons of brain stem

BS.Chat

Serotonergic neurons of brain stem

Bs.Slc6a4

Cerebellum

Cb

Bergman glia and mature oligodendrocytes of cerebellum

Cb.Septin4

Purkinje cells of cerebellum

Cb.Pcp2

Granule cells of cerebellum

Cb.Neurod1

Stellate and basket cells of cerebellum

Cb.Lypd6

Unipolar brush cells and Bergman glia of cerebellum

Cb.Grp

Golgi neurons of cerebellum

Cb.Grm2

Astroglia of cerebellum

Cb.Fthfd

Myelinating Oligodendrocyte of cerebellum

Cb.Cnp

Striatum(Caudate and Putamen)

Cpu

Drd2+ medium spiny neurons of striatum

Cpu.D2

Drd1+ medium spiny neurons of striatum

Cpu.D1

Cholinergic neurons of striatum

Cpu.Chat

Cortex

Ctx

Oligodendrocyte Progenitor Cells of cortex

Ctx.Pdgfrajd340

Immune Cells*

Ctx.Etv1_ts88

Pnoc+ neurons of cortex

Ctx.Pnoc

Ntsr+ neurons of cortex

Ctx.Ntsr

Glt25d2 neurons of cortex

Ctx.Glt25d2

Astrocytes of cortex

Ctx.Fthfd

Cort+ neurons of cortex

Ctx.Cort

Myelinating Oligodendrocyte of cortex

Ctx.Cnp

Habenula (epithalamus)

Epi

Cholinergic neurons of habenula

Epi.Chat

Spinal cord

Spc

Cholinergic neurons of spinal cord

Spc.Chat

*This line was generated to target Layer 5a Corticostriatal interneurons, but gene expression analysis revealed substantial contamination with lymphoid cell data.

Additional Information about these mouse lines and cell types can be found in the following references:

Doyle, J.P. et al. Application of a translational profiling approach for the comparative analysis of CNS cell types. Cell 135, 749-62 (2008).

Dougherty, J.D. et al. Candidate Pathways for Promoting Differentiation or Quiescence of Oligodendrocyte Progenitor-like Cells in Glioma. Cancer research 72, 4856-68 (2012).